The Henderson family return from their vacation and find out they took an eight foot sasquatch named Harry with them. They decide to nurse him, and they end up letting him stay with them.
A football legend visits the Hendersons' house along with his wife who is wearing a fur. Harry thinks that the fur is a dead person and decides to bury it.
While on a camping trip with his son and his co-worker, George is nervous because the co-worker keeps on playing pranks and later mistakes Harry for a monster.
It's Halloween and Harry finally has a chance to get out. However, the Hendersons' neighbour, who is allergic to animal hair, becomes suspicious of Harry's "costume."