| 12:00 AM | Local Programming |
| 12:05 AM | Lost - This Place Is Death: Locke shoulders the burden of ending the island's increasingly violent movements through time. |
| 1:05 AM | Lost - The Life and Death of Jeremy Bentham: Locke's mission off the island as Jeremy is revealed. |
| 2:05 AM | Movie |
| 4:05 AM | Ron Hazelton's House Calls |
| 4:35 AM | To Be Announced |
| 5:00 AM | Storm Stories: True accounts of life-threatening, weather-related events. |
| 5:30 AM | Local Programming |
| 8:00 AM | Good Morning America: News and entertainment. |
| 9:00 AM | Local Programming |
| 10:00 AM | This Week With George Stephanopoulos: Sen. Tom Coburn; Sen. Ben Nelson; Rep. Marsha Blackburn; Rep. Debbie Wasserman Schultz. |
| 11:00 AM | Local Programming |
| 1:00 PM | Our World With Black Enterprise: Kedar Massenburg; the divide between blacks and Latinos; Kimberly Holland. |
| 1:30 PM | Sports Stars of Tomorrow: Top young talent. |
| 2:00 PM | NASCAR Angels: Rusty Wallace and top drivers help deserving people across the nation with their car-care needs. |
| 2:30 PM | NASCAR Countdown |
| 3:15 PM | NASCAR Racing - Sprint Cup: Ford 400 : From Homestead-Miami Speedway in Homestead, Fla. |
| 7:30 PM | America's Funniest Home Videos: A boy tries to free his father, whose arm is stuck in a car's power window. |
| 8:00 PM | 2009 American Music Awards: Fans votes determine which musical acts are honored at the annual ceremony. |
| 11:00 PM | Local Programming |
| 11:35 PM | Grey's Anatomy - Raindrops Keep Falling on My Head: A bartender collapses as Meredith and Cristina lament. |