The track was released on Ross's 1985 album Eaten Alive, and as a single twice - in 1985 and again in 1986.
The song hit No. 1 in Australia and was the top selling single of the year (1986) in that country.
The single became Diana's second No. 1 hit in the UK Singles Chart.
As an Easter egg, on the back wall of the station control room there are photos from live performance by the Supremes.
In 1993, Diana Ross released "Chain Reaction '93". Producing the remix herself, the single was also successful in the United Kingdom. This version's purely instrumental sound differs it from the original. A music video was not recorded for the song.