At the end of the opening credits, the show's tag line "The Truth is Out There" appears. Then it appears a second time, suggesting a doppelganger that is a recurring plot point in the episode.
While filming next to a road, a bear appeared in front of Gillian Anderson. David Duchovny, standing next to her, declared that he thought that he should walk between the bear and Anderson in order to protect her, but then he thought that he didn't want to die.
After visiting Demon Judy, at 18:41 Scully states "To gather the other apes and make war on your dread enemy". Karin Konoval, who portrays Judy, had a recurring role as the orangutan Maurice in the Planet of the Apes franchise.
Sore Points: The opening band at the beginning is from Vancouver, BC. Lyrics are written by David Duchovny.