Opens with the new pharaoh saying he would like Moses to return to Egypt. He sends a messenger to tell Moses to return and he will be given his former titles. This is not recorded as happening in Genesis.
Moses is shown leaving his family with Jethro when he goes back to Egypt. In Genesis it is says he took his wife and his sons with him to Egypt.
Moses is seen first meeting with Pharaoh alone. In Genesis both Moses and Aaron go to see Pharaoh.
In the episode a lower functionary tells the Hebrews to make bricks without straw. In Genesis it is Pharaoh who commands this after Moses and Aaron ask that the Hebrews be allowed to go into the desert for three days to hold a feast to God.