The Power Ponies comic takes place in Maretropolis, which is a pun on the city of Metropolis from Superman, but its color scheme is similar to those used for Gotham City from Batman.
Masked Matter-Horn's name is a pun on the European mountain Matterhorn, and the fact she uses her horn to generate magic and matter.
Filli-Second's name is a pun on "millisecond", referring to her super speed.
The Power Ponies act similar to various superheroes. Masked Matter-Horn is similar to Cyclops, Filli-Second is similar to The Flash, Zapp is similar to Thor and Storm, Radiance is similar to Green Lantern, Mistress Mare-velous is similar to Wonder Woman, and Saddle Rager is similar to the Incredible Hulk. Humdrum is also similar to Batman's sidekick Robin, while the Mane-iac is similar to the Joker, Doctor Octopus, and Medusa.
Friendship Report: Spike learned he doesn't need powers to be a superhero.