- Abigail Hobbs: Will always said whoever called the house that morning was the serial killer... Why did you really call?
- Dr. Hannibal Lecter: I wanted to warn your father that Will Graham was coming for him.
- Abigail Hobbs: Why?
- Dr. Hannibal Lecter: I was curious what would happen... I was curious what would happen when I killed Marissa... I was curious what you would do.
- Abigail Hobbs: You wanted me to kill Nick Boyle.
- Dr. Hannibal Lecter: I was hoping... I wanted to see how much like your father you were.
- Abigail Hobbs: Oh, my God.
- Dr. Hannibal Lecter: Nicholas Boyle is more important for you gutting him... He changed you, Abigail... That's more important than the life he clamored after.
- Abigail Hobbs: How many people have you killed?
- Dr. Hannibal Lecter: Many more than your father.
- Abigail Hobbs: Are you going to kill me?
- Dr. Hannibal Lecter: I'm so sorry, Abigail... I'm sorry I couldn't protect you in this life.
- Abigail Hobbs: Do you ever hunt?
- Will Graham: I fish.
- Abigail Hobbs: It's the same thing, isn't it? One you stalk, the other you lure.
- Will Graham: Were you more a fisherman or a hunter?
- Abigail Hobbs: My dad taught me how to hunt.
- Will Graham: No, that's not what I'm asking. All those girls your dad killed... Did you fish, or did you hunt, Abigail?
- Abigail Hobbs: I was the lure.
- Freddie Lounds: I've interviewed enough killers to know one when I see one.
- Abigail Hobbs: What gives them away?
- Freddie Lounds: A very specific brand of hostility.
- Will Graham: [about Virginia Madchen's death] Listen, something went wrong, and we will never know what that is, but for all the doctors she saw, for all of the help she received, she was fighting that wrong alone.
- Jack Crawford: There is nothing you could do about that.
- Will Graham: All her adult life this woman was misunderstood, and what I can do is make sure that her death isn't misunderstood... She didn't kill herself.