Trevor says he attended the University of Pennsylvania with "the kid who played Chunk in The Goonies (1985)." Jeff Cohen attended the University of California at Berkeley for undergraduate studies and UCLA for law school.
Isaac refers to the barmaid's breasts as "knockers" when talking to Benjamin Franklin. However, the first instance of using the word as slang for breasts wasn't until 1941.
The Freemasons are an English society, rooted in medieval masons, not a fraternity of rich Americans.
Issac's friend in 1773 flashback points out that General Washington has entered the tavern. Washington was not a general until he was appointed commander-in-chief of the Continental Army on June 15, 1775