In an oddity of casting, 47yr old Jason Gedrick (Professor Farnsworth) was actually much closer in age to 50 yr old Teryl Rothery (Madelyn Guthrie) than he was to his characters 33 yr old love interest Erica Cerra (Clarissa).
Richard Harmon and Erica Cerra have both appeared in The 100 as Murphy and Ali, respectively.