In 1986, a pilot for NBC was produced titled "The Greatest American Heroine", which picked up where the ABC series left off. Starring Mary Ellen Stuart as a teacher named Holly Hathaway, Holly is picked by the original characters to take up Ralph's mantle. The pilot failed to be picked up as a series, and was re-edited into the original show's syndication package as the "final episode."
In May 11, 2018 ABC announced that this pilot was not picked up as a series. Many television pundits expected the Nahnatchka Khan-produced project to be an almost sure thing, especially after they landed Hannah Simone, who was one of the 2018 pilot season's most heavily sought out actresses.
Fox developed a Greatesy American Hero one in 2014 with Phil Lord and Chris Miller.