Title of episode comes from the Wordsworth poem "The Solitary Reaper."
Lady Margaret Hall, the Oxford college which is the location of "Lady Matilda's" in this episode, was the first women's college in the University. It has admitted men since 1979.
From Wordsworth poem "The Solitary Reaper" (1807): "Behold her, single in the field, Yon solitary Highland Lass! ... Will no one tell me what she sings?... Perhaps the plaintive numbers flow For old, unhappy, far-off things, And battles long ago: Or is it some more humble lay, Familiar matter of to-day? Some natural sorrow, loss, or pain, That has been, and may be again?"
The "Endeavour" episode entitled "Arcadia", set in Oxford some 44 years before this "Lewis" episode (and also scripted by Russell Lewis), also makes use of the "House Beautiful" mansion, using the same building as a location; there, however, it is a hippy commune.
The fictitious "Lady Matilda's" college also features in the "Endeavour" episode entitled "Muse", which repeats the idea of referring to a female graduate of the college as a "Matila beast", pronounced quickly so as to rhyme with "wildebeest".