Jensen Ackles, who plays Soldier Boy, makes his first appearance in a Captain America style uniform. Ackles was on the shortlist of actors that were in mind to play Captain America for Marvel Studios when casting for Captain America: The First Avenger (2011).
The CIA operation described by Grace Mallory in this episode is inspired by the real-life involvement of the CIA in Contra's cocaine trafficking operation.
The actor who plays young Gunpowder in the flashback scenes, Gattlin Griffith, played Jesse Turner/Antichrist in I Believe the Children Are Our Future (2009) a Season 5 episode of Supernatural (2005), Jensen Ackles' signature series. Ackles plays Soldier Boy on "The Boys".