While discussing the initial patient's diagnosis with the rest of his team in his office, House is eating a bagel that begins as sesame when removed from the bag, is plain when he takes a bite, and is sesame again as he chews it.
Immediately after a hemispherectomy, patients will not be buttoning their own shorts or walking out of the hospital because one side of their body will be paralyzed until the other brain hemisphere learns to take over for the one that was removed, which will take weeks and intense therapy.
House says "dude can't button a shirt" referring to the "half wit" But was not in the scene that shows the "half wit" not being able to button his shirt.