This show originated from Chicago, Illinois, where John Daly was covering the Democratic National Convention for ABC News. It was one of only two shows to be produced outside of New York during its 17 1/2-year run on CBS.
Perle Mesta was a last-minute substitute mystery guest, after a proposed mystery guest appearance by former President Harry S. Truman was vetoed by former General Douglas MacArthur who was Chairman of the Board of Remington Rand, one of the show's co-sponsors, at the time.