At the bowling alley, Rube bowls a 9, his next ball is to a clean set of pins for a strike, he should have been bowling for a spare.
In the bowling alley flashback, George's younger self has blue eyes, whereas George has brown eyes.
As Rube says "If you don't mind me asking..." to Joy in the waiting room, Joy changes from holding her book by the cover, to by the spine between shots.
The second time George bowls with her coworkers, we see two flashbacks of her bowling with her mother. They are of the same event yet in the first flashback her mother is wearing a pink shirt, in the second flashback she's wearing a blue shirt.
When Rube looks at the doctors' appointment list, there is no one named "Lass" registered - yet Reggie and her mother are already there for a session.
Reggie finds distinctive floral purple and yellow bedlinen in George's old boxes and puts it on her own bed, as referenced by Joy when she enters Reggie's room. Daisy buys exactly the same bedlinen and puts it on George's apartment bed, yet George shows no sign of recognising the bedlinen that used to be in her own bedroom when she was alive.
May not be a mistake but a lie the character tells. She claims to have died on the set of 'Gone with the Wind' but is later revealed to have died December 13, 1938, in Marietta, Georgia. 'Gone with the Wind' was filmed entirely in California, from January to June 1939.