- Continuity: During Maggie's first fight, the manager takes her mouthpiece and rinses it but never gives it back to her.
- Errors in geography: When Maggie is taking her mother to the new home she just bought her, there are palm trees around the other houses in the neighborhood. This scene is supposed to be in a small town in Missouri, where palm trees do not grow.
- Continuity: The "Everlast" patch on the speed bag moves repeatedly between shots after Frankie begins to train Maggie (the last half of the speed bag scene).
- Crew or equipment visible: When Frankie introduces Maggie to one of the managers at the gym, movie lights can be seen reflected in the sunglasses hanging on his shirt.
- Crew or equipment visible: When Maggie is training with Frankie in the ring, you can see the power pack on her back.
- Continuity: When Eddie is reading a magazine, while on his bed, Frankie enters the Gym with a hamburger. Eddie throws the magazine on the bed to see who has entered. The magazine is seen on the pillow, wide open. The magazine is next seen closed and almost out of sight.
- Continuity: When Maggie is sparring at the gym before her first fight, Frankie calls her over to talk. Her ponytail changes position from down her back to over her shoulder between front and back shots.
- Revealing mistakes: When Frankie is training Willy in the ring, Maggie walks in to begin training. She is carrying a new, expensive Ogio gym bag even though she's supposed to be so poor she has to scrape change together to buy a speed bag.
- Continuity: Whilst Maggie is being ventilated her right eye is swollen up really bad, the next clip her right eye is fine and her left eye seems to be bloated instead.
- Errors made by characters (possibly deliberate errors by the filmmakers): Eddie Dupris claims that a knockout is caused when the neck turns a certain degree after which the human body takes over and shuts itself down for safety reasons. While generally unknown, it is widely believed that a knockout is actually caused by the rattling of the brain against the skull causing severe trauma resulting in a concussion.
- Factual errors: The back of Molly's robe has the phrase "Mo Cuishle". However the correct spelling in Irish Gaeilge is "Mo Chuisle".
- Errors in geography: When Frankie & Maggie leave Maggie's hometown of Theodosia, MO, they pass a road sign with "160" inside a Missouri outline, the correct sign for Missouri State Highway 160. However, the main highway through real-life Theodosia (in far southern Missouri, just north of the Arkansas border and east of Branson) is U.S. Highway 160.
- Anachronisms: Maggie's opponent in the movie is said to be the East German Champion but the German flag shown at the championship fight is not the East German flag. The flag shown in the movie is the flag of the united Germany - a black, red and gold tricolor without any symbols on it - that flag was never used by East Germany. The East German flag however was black, red and gold with the socialist symbol of hammer and compass on it.
>>> WARNING: Here Be Spoilers <<<
Goofs below here contain information that may give away important plot points. You may not want to read any further if you've not already seen this title.
- Continuity: SPOILER: When Frankie removes Maggie's ventilator to administer a lethal dose of adrenaline, she is clearly breathing on her own. Earlier in the movie, Eddie's voice-over noted that Maggie will never be able to breathe on her own again.
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