Because of budget constraints, Marshall Efron was the only person to appear on-camera. A "crowd scene" was shot by having Efron walking past a camera multiple times in different costumes, and the images were superimposed on top of each other. When a scene required two or more people to appear, Efron would have scenes shot with him speaking to someone off-camera or to a dummy with its back to the camera. Corresponding scenes then would be shot, with Efron playing the other role. The footage would be edited to make Efron appear to talk to himself.
Efron created the title by studying the elaborate labels on antique patent medicine bottles.
Marshall Efron had the idea for the format when he saw actor Richard Loo performing a one man version of Hamlet on stage.
According to Marshall Efron, he had wanted one segment to be the account of the resurrection of Lazarus, with the character painted green and groaning like the Frankenstein monster, but the network rejected it on the grounds it would frighten children.