According to Chris Kattan, after completing the film, Will Ferrell didn't speak to Kattan again until the 23rd season of Saturday Night Live due to an on set relationship between Kattan and producer Amy Heckerling having upset Ferrell. Kattan alleged that Ferrell had said "so, I got all your messages, but I didn't call you back because I didn't want to talk to you." The production of this film caused the end of their friendship, which had started when they were both members of the Groundlings. They worked together on SNL until Ferrell left at the end of season 27, but have never collaborated on anything since then.
The dance routine Doug and Steve perform with Cambi and Vivica at their first night at the Roxbury is the same as the one Vinnie and Barney and two ladies perform in the club scene in My Blue Heaven (1990).
Will Ferrell married co-star Viveca Paulin in 2000. As of 2018, this is the only film that the two have appeared in together.