Joan Sims was originally cast in the title role but put on weight before production started. Producer Peter Rogers recast the part with Juliet Mills but offered Sims any other role for a higher salary, and she chose the part of Deborah, the vicar's daughter.
Abel Worthy's general store was a fake frontage built on a driveway between two existing houses, one of which was used as Abel's house.
In 2007 the movie's owner, Studio Canal, made a digital transfer which aired on UK television and was used on a DVD release. However, two reels were transposed making the middle part of the story largely unintelligible. In particular, Henry and Joanna are together on the rounds before Henry has said he will do it; Deborah cuts Joanna dead with no explanation; Miss Maitland is working as the doctor's secretary before he advertised the job; an inexplicable wild driving sequence involving Henry and Joanna is suddenly cut and not mentioned, it then resumes some 10 minutes later. Studio Canal allegedly fixed the problem in 2020 but the incorrect version was still being shown on UK Television in October 2022.
Four actors worked previously on another medical based comedy released a year earlier Twice Round the Daffodils (1962), they were Juliet Mills, Ronald Lewis, Joan Sims and Amanda Reiss.