Dr. Cory, under the control of the brain, makes out a list showing several false identities under which Donovan has hidden money around the country. The first four names on the list are actual names of crew members: production supervisor H.B. Chapman, production designer Boris Leven, assistant director Jack R. Berne (on list as "Jack Byrne") and set decorator Edward Boyle. The fifth name, Fred Russell, is that of a popular sports writer of the early 1950s.
Orson Welles played the part of Dr. Corey in "Donovan's Brain" on the only two-part broadcast ever produced on radio's "Suspense", 18 May and 25 May 1944.
The sign on the door of the attorney's office includes a "B. Chapman, CPA." Ben Chapman was the film's production supervisor.
Writer Curt Siodmak was also set to direct, but at the last minute he was replaced by Felix E. Feist.
The second of three versions of Curt Siodmak's famous novel to be made in a period of less than twenty years, and the only one to retain the original title. Although this is, all in all, the version of "Donovan's Brain" which stays closest to the classic original, it is most noticeable that Dr. Corey is here a warm-hearted and humorous man, devoted to his wife and to his hard-drinking friend Schratt; in the novel, Corey is a ruthless, cold-blooded, unfeeling fellow who treats all around him with contempt.