Sort by Popularity - Most Popular Movies and TV Shows tagged with keyword "mind-altering-drug"

1. John Dies at the End (2012)

R | 99 min | Comedy, Fantasy, Horror

A new street drug that sends its users across time and dimensions has one drawback: some people return no longer human. Can two college drop-outs save humanity from this silent, otherworldly invasion?

Director: Don Coscarelli | Stars: Chase Williamson, Rob Mayes, Paul Giamatti, Clancy Brown

Votes: 40,378 | Gross: $0.14M

2. Far Cry 5 (2018 Video Game)

M | Action, Adventure, Crime

A deputy is sent to the town of Hope County to arrest Joseph Seed, a corrupt evangelical religious leader who rules the town with the help of his disturbed followers.

Director: Patrick Methe | Stars: Greg Bryk, Mark Pellegrino, Seamus Dever, Jenessa Grant

Votes: 9,087

3. Wormwood (2017)

40 min | Documentary, Biography, Drama

In 1953, Army scientist Frank Olson takes a fatal plunge from a hotel window. In 1975, a bombshell report ties his death to a top-secret experiment.

Stars: Peter Sarsgaard, Molly Parker, Christian Camargo, Scott Shepherd

Votes: 4,713

4. Edge of Sanity (1989)

R | 90 min | Drama, Horror, Thriller

When Henry Jekyll's experiments with cocaine have gotten out of control, he transforms into the hideous Jack Hyde. As Hyde he searches the London streets at night for his prey in ... See full summary »

Director: Gérard Kikoïne | Stars: Anthony Perkins, Glynis Barber, Sarah Maur Ward, David Lodge

Votes: 1,806 | Gross: $0.10M

5. Evil Bong 420 (2015)

Not Rated | 53 min | Comedy, Horror

When Rabbit escapes Evil Bong's evil world, he opens a bowling alley, and decides to have a celebration with friends. Little does Rabbit know that not only is Evil Bong on his trail, he's ... See full summary »

Director: Charles Band | Stars: Sonny Carl Davis, John Patrick Jordan, Robin Sydney, Amy Paffrath

Votes: 497

6. Red Roses of Passion (1966)

85 min | Crime, Drama, Fantasy

Jaded Carla drugs her stuck up aunt and her daughter with mind-altering aphrodisiac concocted from a rose by an ominous Pan sex cult. The women become crazed nymphos and the only way to cure them is for Carla to give herself to "Pan".

Director: Joseph W. Sarno | Stars: Judson Todd, Jean James, Carol Holleck, Helena Clayton

Votes: 224

7. Crack-Up (1946)

Approved | 93 min | Crime, Drama, Film-Noir

Art curator George Steele experiences a train wreck...which may not have actually happened. Is he cracking up, or the victim of a wicked plot?

Director: Irving Reis | Stars: Pat O'Brien, Claire Trevor, Herbert Marshall, Ray Collins

Votes: 1,629

8. Hyde (2025)

Drama, Horror, Thriller | Filming

A modern re-imagining of the classic story, based on the novella by Robert Louis Stevenson.

Director: Matthew Winstead | Stars: David Draper Jr., Avra Sullivan, Conner Parker, Daniel MacFarland Jr.

9. The Skin of the Teeth (2018)

Unrated | 80 min | Drama, Thriller

After his date takes a shocking turn, a man is plunged into a surreal interrogation of just who and what he is.

Director: Matthew Wollin | Stars: Pascal Arquimedes, Donal Brophy, Tom Rizzuto, Chuja Seo

Votes: 107

10. The Outer Limits (1995–2002)
Episode: Hearts and Minds (1998)

TV-PG | 45 min | Drama, Fantasy, Horror

Soldiers are on a mission to kill aliens on a distant planet to protect a mineral necessary and profitable for Earth. The soldiers are injected with a drug to enhance their abilities which has consequences when the drug wears off.

Director: Brad Turner | Stars: Christine Elise, Miguel Fernandes, Dylan Walsh, Vincent Gale

Votes: 278

11. Jack of All Trades (2000)
Episode: The Morning After (2000)

22 min | Adventure, Action, Comedy

After sampling a special wine, Emilia and Jack wake up in bed together with no memory of how they got there. They discover that Napoleon is planning on sending that wine to all the world ... See full summary »

Director: Michael Hurst | Stars: Bruce Campbell, Angela Marie Dotchin, Verne Troyer, Stuart Devenie

Votes: 62

12. Curious Life and Death of .. (2020– )
Episode: A Rolling Stone (2020)

TV-14 | Documentary, Biography, Mystery

Dr Lindsey Fitzharris explores the mysterious death of Brian Jones, founder of the Rolling Stones, looking at the role that drink, drugs and rock'n'roll played, and whether there is evidence of murder.

Director: Toby Roebuck | Stars: Lindsey Fitzharris, Brian Jones, The Rolling Stones, Mick Jagger

Votes: 13

13. Hamilton's Pharmacopeia (2011– )
Episode: Shepherdess: The Story of Salvia Divinorium (2016)

TV-MA | 43 min | Documentary

From the heavenly cloud forests of Oaxaca to a viral video of Miley Cyrus, Hamilton investigates the inconspicuous yet extraordinary psychedelic plant Salvia divinorum.

Director: Danilo Parra | Stars: Hamilton Morris, Jose Luis Diaz, Erik Hoffstad, James Lange

Votes: 64