She was diagnosed with breast cancer on November 22, 2016. She subsequently started presenting the podcast You, Me and the Big C to raise awareness of cancer, discussing the disease with celebrities and providing advice of how to manage it. In May 2018, she announced that her cancer had spread and was now incurable. She participated in a clinical trial of a new treatment. On September 3, 2018, Bland announced on her Twitter account that her "time had come", and that she only had days to live. She died two days later at the age of 40. You, Me and the Big C reached number one on the iTunes Podcast charts during this week.