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- CreatorDavid CraneMarta KauffmanStarsJennifer AnistonCourteney CoxLisa KudrowFollows the personal and professional lives of six twenty to thirty year-old friends living in the Manhattan borough of New York City.
- CreatorDavid ShoreStarsHugh LaurieOmar EppsRobert Sean LeonardUsing a crack team of doctors and his wits, an antisocial maverick doctor specializing in diagnostic medicine does whatever it takes to solve puzzling cases that come his way.
- CreatorChuck LorreBill PradyStarsJohnny GaleckiJim ParsonsKaley CuocoAspiring film actress Penny Teller moves into a Pasadena apartment across the hall from brilliant, but socially awkward, physicists Sheldon Cooper and Leonard Hofstadter and shows them how little they know about life outside of the lab.
- CreatorEric KripkeStarsJared PadaleckiJensen AcklesJim BeaverTwo brothers follow their father's footsteps as hunters, fighting evil supernatural beings of many kinds, including monsters, demons, and gods that roam the earth.
- CreatorCarter BaysCraig ThomasStarsJosh RadnorJason SegelCobie SmuldersA father recounts to his children - through a series of flashbacks - the journey he and his four best friends took leading up to him meeting their mother.
- CreatorMark Edward EdensSidney IwanterEric LewaldStarsCedric SmithCal DoddLenore ZannA team of mutant superheroes fight for justice and human acceptance in the Marvel Comics universe.
- CreatorMasashi KishimotoStarsAlexandre CrepetJunko TakeuchiMaile FlanaganNaruto Uzumaki, is a loud, hyperactive, adolescent ninja who constantly searches for approval and recognition, as well as to become Hokage, who is acknowledged as the leader and strongest of all ninja in the village.
- CreatorStan LeeSteve DitkoStarsChristopher Daniel BarnesSara BallantineEdward AsnerA young man with spider-like abilities fights crime as a superhero in New York City while trying to have a normal personal life.
- CreatorHart HansonStarsEmily DeschanelDavid BoreanazMichaela ConlinF.B.I. Special Agent Seeley Booth teams up with the Jeffersonian's top anthropologist, Dr. Temperance Brennan, to investigate cases where all that's left of the victims are their bones.
- CreatorPaul GermainJoe AnsolabehereStarsAndrew LawrenceAshley JohnsonJason DavisComic tales of a group of good friends, four boys and two girls, during breaks in primary school, as they grow up, relate to each other, and have brushes with authority.
- CreatorMasashi KishimotoStarsJunko TakeuchiMaile FlanaganKate HigginsNaruto Uzumaki, a mischievous adolescent ninja, struggles as he searches for recognition and dreams of becoming the Hokage, the village's leader and strongest ninja.
- CreatorRumiko TakahashiStarsKappei YamaguchiRichard Ian CoxSarah HauserA teenage girl periodically travels back in time to feudal Japan to help a young half-demon recover the shards of a jewel of great power.
- CreatorMatt NixStarsJeffrey DonovanGabrielle AnwarBruce CampbellA spy recently disavowed by the U.S. government uses his special ops training to help others in trouble.
- CreatorJoseph BarberaWilliam HannaStarsAlan ReedMel BlancJean Vander PylThe misadventures of two modern-day Stone Age families, the Flintstones and the Rubbles.
- CreatorDavid SlackBob HaneyBruno PremianiStarsHynden WalchGreg CipesScott MenvilleA team of five teenaged superheroes save the world from many villains around their city while experiencing things normal teens face today.
- StarsJohn ErwinAlan OppenheimerLinda GaryThe most powerful man in the universe, He-Man, goes against the evil forces of Skeletor to save the planet Eternia and to protect the secrets of Castle Grayskull.
- CreatorAlfred GoughMiles MillarStarsTom WellingMichael RosenbaumAllison MackA young Clark Kent struggles to find his place in the world as he learns to harness his alien powers for good and deals with the typical troubles of teenage life in Smallville, Kansas.
- CreatorPeter M. LenkovAlex KurtzmanLeonard FreemanStarsAlex O'LoughlinScott CaanTaylor WilyWhen Steve McGarrett returns home to Oahu to find his father's killer, the Governor offers him the chance to run his own task force: Five-0.
- CreatorRhode MontijoKenn NavarroAubrey AnkrumStarsDavid WinnEllen ConnellWarren GraffA series of horrible sudden deaths keep happening to a group of creatures caused by themselves doing the most stupid things.
- CreatorDarren StarStarsSarah Jessica ParkerKim CattrallKristin DavisFour female New Yorkers gossip about their sex lives (or lack thereof) and find new ways to deal with being a woman in the late 1990s.
- CreatorPeter HannanStarsJim CummingsTom KennyCarlos AlazraquiThe life and times of a cat and a dog with a unique twist: they're connected, literally. Adding to their dilemma is Cat's annoyance with Dog, mainly caused by Dog's stupidity and Cat's up-tight personality.
- CreatorAnn DonahueCarol MendelsohnAnthony E. ZuikerStarsDavid CarusoEmily ProcterAdam RodriguezAn elite unit, led by an ex-homicide cop, which is linked to the Miami-Dade Police Department, uses all possible resources and skills at their disposal to solve complex crimes in cross-cultural Miami.
- CreatorTrey ParkerMatt StoneBrian GradenStarsTrey ParkerMatt StoneIsaac HayesFollows the misadventures of four irreverent grade-schoolers in the quiet, dysfunctional town of South Park, Colorado.
- CreatorDavid X. CohenMatt GroeningStarsBilly WestJohn DiMaggioKatey SagalPhilip J. Fry, a pizza delivery boy, is accidentally frozen in 1999 and thawed out on New Year's Eve 2999.
- CreatorPeter ReesStarsRobert LeeJamie HynemanAdam SavageA weekly documentary in which two Hollywood special effects experts attempt to debunk urban legends by directly testing them.