The university that the students attend was also used as the setting for several other films including Urban Legend (1998) and The Skulls (2000). Coincidentally all three films starred Joshua Jackson.
Lena Headey, James Marsden, and Norman Reedus were all in their late twenties when filming this movie. Out of the main cast, only Kate Hudson and Joshua Jackson were in the typical college student age group.
Brittany Murphy and Reese Witherspoon were considered for the role of Naomi Preston. Jennifer Love Hewitt and Maggie Gyllenhaal were considered for the role of Jones.